Original Articles

Five years survival and quality of life after radical nephrectomy: a descriptive single-center study

Adryansyah Can , Ginanda Putra Siregar, Bungaran Sihombing, Fauriski Febrian Papriska, Syah Mirsa Warli

Adryansyah Can
Department of Urology, Faculty of Medicine Universitas Sumatera Utara-Universitas Sumatera Utara Hospital, Medan, Indonesia. Email: gregadryan@gmail.com

Ginanda Putra Siregar
Department of Urology, Faculty of Medicine Universitas Sumatera Utara-Universitas Sumatera Utara Hospital, Medan, Indonesia

Bungaran Sihombing
Department of Urology, Faculty of Medicine Universitas Sumatera Utara-Universitas Sumatera Utara Hospital, Medan, Indonesia

Fauriski Febrian Papriska
Department of Urology, Faculty of Medicine Universitas Sumatera Utara-Universitas Sumatera Utara Hospital, Medan, Indonesia

Syah Mirsa Warli
Department of Urology, Faculty of Medicine Universitas Sumatera Utara-Universitas Sumatera Utara Hospital, Medan, Indonesia
Online First: June 22, 2021 | Cite this Article
Can, A., Siregar, G., Sihombing, B., Papriska, F., Warli, S. 2021. Five years survival and quality of life after radical nephrectomy: a descriptive single-center study. Indonesia Journal of Biomedical Science 15(1): 75-79. DOI:10.15562/ijbs.v15i1.306


Introduction: Health-related quality of life (QoL) is an increasingly important factor in examining the benefits of different cancer treatments, such as radical nephrectomy for those with a renal mass presumed to be renal cell carcinoma (RCC). This study evaluates five years of survival rate, and quality of life of the patient after radical nephrectomy in our center.

Methods: This descriptive longitudinal study included thirty patients who were diagnosed as having renal mass in Urology division of H. Adam Malik General Hospital between January 2014 and December 2015. All patients were completely followed up for 5 years or until the patient died. We used a translated and validated Indonesian written European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Version 3.0 (EORTC QLQ-C30) to assess the patient’s quality of life.

Results: Overall, 5-years survival of kidney tumor patients was 100%, 66.67%, 50%, 8.33%, respectively for stages 1 to 4. We found a sharp decrease in the cumulative survival rate of stage IV group in the first 24 months compared to the first 12 months, from 66.67% to 25%. This pattern of decrease was not found in the other group of stages. Overall, patients' quality of life had increased in the first three years postoperatively and decreased in the two years afterward. These fluctuations consistently occur in all groups. All of the groups had reached the maximum quality of life at the third year postoperatively.

Conclusion: Stage I renal cell carcinoma patients showed the best five-year survival rate and quality of life. The quality of life for all groups inclined for the first three years after surgery and decline consistently afterward.

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