Case Reports

A case of Nevus of Ota treated with laser picosecond Alexandrite 755 nm: A case-report

Ketut Kwartantaya Winaya , I Made Setiadji

Ketut Kwartantaya Winaya
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Udayana / Sanglah Hospital, Denpasar, Bali, Indonesia. Email:

I Made Setiadji
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Udayana / Sanglah Hospital, Denpasar, Bali, Indonesia
Online First: August 01, 2021 | Cite this Article
Winaya, K., Setiadji, I. 2021. A case of Nevus of Ota treated with laser picosecond Alexandrite 755 nm: A case-report. Indonesia Journal of Biomedical Science 15(2): 101-105. DOI:10.15562/ijbs.v15i2.326

Background: Nevus of Ota is a well-defined dermal melanocytosis characterized by bilateral multiple small, bluish-brown macules in the area innervated by the first and second branches of the trigeminal nerve. Currently, the therapeutic modalities for this condition are still limited and complete resolution is difficult to achieve.

Case Description: A 23-year-old woman complained a brown spot on the right cheek since the patient was born. It looked like the skin but slightly darker than its surroundings. Four years ago the patient had received 6 sessions of QS: Nd-YAG laser therapy, but the spot is still clearly visible. Dermatological status of the orbital, infraorbital, zygomatic, and right buccal regions showed multiple hyperpigmented patches, gray-brown, well-defined, geographically in shape with size 0.2 x 0.3cm – 5 x 7cm. The lesion was unilateral and distributed within the innervation area of the second and third trigeminal nerve. Miravex® skin analysis showed that the average level of melanin was 0.464 with a melanin variation of 45%. Therefore, patient was diagnosed with Nevus of Ota. The proposed treatment was  picosecond alexandrite 755nm laser, with a frequency of 2.5 Hz, pulse duration 550-750 ps, spot size 4 mm, and fluence 1.59 J/cm2. A marked improvement was observed after the treatment and after 21 days, a good grade of improvement was reported.

Conclusion: Nevus of Ota can effectively treated with 755nm picosecond alexandrite laser therapy and results in a good grade of improvement.


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