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Leukocytospermia is related to total motile sperm counts in infertile men at Sadewa Maternal and Child Hospital, Yogyakarta, Indonesia


Background: Leukocytospermia is defined as the presence of leukocytes in semen at the concentration of ? 1 x 106/mL according to World Health Organization (WHO) manual procedure. Leukocytes are the source of reactive oxygen species (ROS), which may lead to oxidative stress conditions and sperm damage. This study aims to evaluate the association between leukocytospermia, poor semen quality, and infertility at Sadewa Maternal and Child Hospital, Yogyakarta, Indonesia

Methods: This study was based on secondary data of semen analyses of males attending IVF clinics at Sadewa Maternal and Child Hospital, Yogyakarta, Indonesia, from May 2015 to November 2020. Variables assessed in this study were semen volume, sperm concentration, progressive motility, and Total Motile Sperm Count (TMSC). Data were analyzed using SPSS version 23 for Windows.

Results: The median sperm concentration of the leukocytospermia group was higher than that of the non-leukocytospermia group. There is a relationship between the number of leukocytes in semen and TMSC, with the higher TMSC median in the leukocytospermia group.

Conclusion: This is the first study to report a significant association between leukocytospermia and total motile sperm count (TMSC). The association is not expected with leukocytospermia patients who have better TMSC value.



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How to Cite

Rizal, D. M., Hartanto, M. C., & Septiyorini, N. (2021). Leukocytospermia is related to total motile sperm counts in infertile men at Sadewa Maternal and Child Hospital, Yogyakarta, Indonesia. Indonesia Journal of Biomedical Science, 15(2), 155–158.




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Dicky Moch Rizal
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Markus Christian Hartanto
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Nandia Septiyorini
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