Original Articles

Analysis of factors associated with the incidence of neonatal asphyxia in the neonatal intensive care unit (NICU) and perinatology unit in Wangaya Regional General Hospital

Ni Kadek Risa Astria , Wayan Bikin Suryawan, Anak Agung Made Sucipta

Ni Kadek Risa Astria
General doctor, Wangaya Regional General Hospital, Denpasar, Bali. Email: risaastria95@gmail.com

Wayan Bikin Suryawan
Pediatrician, Department of Pediatric Health, Wangaya Regional General Hospital, Denpasar, Bali

Anak Agung Made Sucipta
Pediatrician, Department of Pediatric Health, Wangaya Regional General Hospital, Denpasar, Bali
Online First: October 05, 2021 | Cite this Article
Astria, N., Suryawan, W., Sucipta, A. 2021. Analysis of factors associated with the incidence of neonatal asphyxia in the neonatal intensive care unit (NICU) and perinatology unit in Wangaya Regional General Hospital. Indonesia Journal of Biomedical Science 15(2): 117-120. DOI:10.15562/ijbs.v15i2.344


Background: Neonatal asphyxia is the second leading cause of neonatal death in Indonesia. According to the World Health Organization (WHO), neonatal asphyxia is the failure of neonates to begin and maintain normal breathing. Neonatal asphyxia can be caused by several factors, namely neonatal, maternal, placental, and delivery factors. This study is aimed to describe the factors associated with the incidence of neonatal asphyxia in Wangaya General Hospital.

Methods: This study used an analytical method with a cross-sectional design. Data for the study were obtained from medical records. Study samples were selected using a simple random sampling technique, and the number of samples included was 170 neonates. The dependent variable was neonatal asphyxia, while the independent variables were preterm gestation, low birth weight baby, premature rupture of membrane, and delivery requiring the procedure. Data were analyzed with bivariate and multivariate analysis on SPSS.

Results: The risk factors that showed association with neonatal asphyxia were preterm gestation (p=0.000; PR= 6.87; 95% CI: 3.19-14.79), low birth weight (p=0.000; PR=9.55; 95% CI 4.14-22.01), and premature rupture of membrane (p=0.002; PR=3.06; 95% CI: 1.48-6.3). while delivery requiring procedure was found to have no significant association with neonatal asphyxia (p=0.219, PR=0.64; 95% CI: 0.31-1.31). On multivariate analysis, it was found that preterm gestation, low birth weight, and premature rupture of membrane all showed significant association with neonatal asphyxia.

Conclusion: There was a significant association between preterm gestation, low birth weight, and premature rupture of the membrane with neonatal asphyxia in Wangaya Regional General Hospital.

References

World Health Organization. Global health observatory (GHO) data: neonatal mortality [Internet]. World Health Organization. 2016 [cited Aug 15, 2021]. Available from: https://www.who.int/data/gho/data/themes/topics/topic-details/GHO/neonatal-mortality-and-causes-of-death

Kardana IM. Risk factors of perinatal asphyxia in the term newborn at Sanglah General Hospital, Bali-Indonesia. Bali Medical Journal. 2016;5(1):175-8.

Kemenkes RI. Profil kesehatan Indonesia tahun 2019 [Internet]. Kementerian Kesehatan Republik Indonesia. 2020 [cited 15th of August, 2021]. Available from: https://pusdatin.kemkes.go.id/resources/download/pusdatin/profil-kesehatan-indonesia/Profil-Kesehatan-indonesia-2019.pdf

Abdo RA, Halil HM, Kebede BA, et al. Prevalence and contributing factors of birth asphyxia among the neonates delivered at Nigist Eleni Mohammed memorial teaching hospital, Southern Ethiopia: a cross-sectional study. BMC Pregnancy and Childbirth. 2019;19(1):1-7.

Lestary DI, Sulaeman ES, Suryani N. Path analysis on the determinants of neonatal asphyxia at Dr. Saiful Anwar Hospital, Malang. Journal of Epidemiology and Public Health. 2016;1(2):140-7.

Salmarini DD, Dona S, Azhari FN. Analysis of the incidence asphyxia neonatorum at Ansari Saleh General Hospital Banjarmasin. Dinamika Kesehatan: Jurnal Kebidanan dan Keperawatan. 2017;8(2):454-62.

Santos NCP, Vogt SE, Duarte ED, et al. Factors associated with low Apgar in newborns in birth center. Rev Bras Enferm. 2019;72(3):297-304.

Dassah ET, Odoi AT, Opoku BK. Stillbirths and very low Apgar scores among vaginal births in a tertiary hospital in Ghana: a retrospective cross-sectional analysis. BMC Pregnancy and Childbirth. 2014;14:289.

Woday A, Muluneh A, St Denis C. Birth asphyxia and its associated factors among newborns in public hospital, northeast Amhara, Ethiopia. PLoS ONE. 2019;14(12): e0226891.

Purwaningsih Y, Dewi YLR, Indarto D, et al. Factors associated with newborn asphyxia at Dr. Harjono Hospital, Ponorogo, East Java. Journal of Maternal and Child Health. 2018 Aug 8;3(4):287-93.

Opitasari C, Andayasari L. Maternal education, prematurity and the risk of birth asphyxia in selected hospitals in Jakarta. Health Science Journal of Indonesia. 2015;6(2):111-5.

Dassios T, Vervenioti A, Dimitriou G. Respiratory muscle function in the newborn: a narrative review. Pediatr Res. 2021;1-8.

Razak R, Adisasmita A. Low birth weight and asphyxia neonatorum risk: a case-control study. Advances in Health Sciences Research. 2020;25:384-7.

Aslam HM, Saleem S, Afzal R, et al. Risk factors of birth asphyxia. Italian Journal of Pediatrics. 2014 Dec;40(1):1-9.

Gudayu TW. Proportion and factors associated with low fifth minute Apgar score among singleton newborn babies in Gondar University referral hospital; North West Ethiopia. African Health Sciences. 2017 May 23;17(1):1-6.

Meshesha AD, Azage M, Worku E, et al. Determinants of birth asphyxia among newborns in referral hospitals of Amhara National Regional State, Ethiopia. Pediatric Health, Medicine and Therapeutics. 2020;11:1-9.

Xia H, Li X, Li X, et al. The clinical management and outcome of term premature rupture of membrane in East China: results from a retrospective multicentre study. International Journal of Clinical and Experimental Medicine. 2015;8(4):6212.

Bayih WA, Yitbarek GY, Aynalem YA, et al. Prevalence and associated factors of birth asphyxia among live births at Debre Tabor General Hospital, North Central Ethiopia. BMC pregnancy and childbirth. 2020;20(1):1-2.

Sadeghnia A, Mohammadpoor S. The investigation of rate of birth asphyxia and its relationship with delivery mode at Shahid Beheshti Hospital of Isfahan during 2013, 2014, and 2015. International Journal of Preventive Medicine. 2019;10:23-32.


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