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Prevalence and prognosis from the disability related to spinal tuberculosis: a systematic review

Abstract

Objective: To review the disabilities caused by Spinal TB in relation to the prevalence and prognosis of the disabilities caused by the disease.

Method: We conducted systematic search of the literatures based on PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and PICO criteria. Our inclusion criteria were: 1) Patients with spinal TB; 2) full original articles; 3) articles written in English; 4) the period of publication of articles from 2012 to 2022. Evaluation of each article was done by checklist Strengthening the Reporting of Observational Studies in Epidemiology (STROBE).

Results: From all articles in the publication year of 2012 to 2022, we reviewed five retrospective cohort studies, all studies coming from Asian countries. The five articles observed the prevalence of disabilities caused by spinal TB reflected through some important outcome variables pre-treatment, where they continued to compare with the post-treatment outcome variables. All of the studies reviewed had agreed that immediate or delayed treatment would give significant benefits to the patients of spinal TB, even better with combined treatments of conventional pre-operative anti-TB drugs and surgical intervention. It was found that poor prognosis associated with preoperative neurological status of the patients.

Conclusion: Conventional anti-TB drugs and surgical intervention can be of great help and benefit for patients with spinal TB, reducing their disabilities severity and improving their prognosis.

Section

References

  1. WHO. Global tuberculosis report 2020. Geneva; 2020
  2. Garg RK, Somvanshi DS. Spinal tuberculosis: a review. J Spinal Cord Med. 2011;34(5):440-54.
  3. Rajasekaran S, Soundararajan DCR, Shetty AP, Kanna RM. Spinal Tuberculosis: Current Concepts. Global Spine J. 2018 Dec;8(4 Suppl):96S-108S.
  4. Alene KA, Wangdi K, Colquhoun S, Chani K, Islam T, Rahevar K, Morishita F, Byrne A, Clark J, Viney K. Tuberculosis related disability: a systematic review and meta-analysis. BMC Med. 2021 Sep 9;19(1):203
  5. Leonardi M, Bickenbach J, Ustun TB, Kostanjsek N, Chatterji S. The definition of disability: what is in a name? Lancet. 2006;368:1219–21.
  6. Jain AK. Treatment of tuberculosis of the spine with neurologic complications. Clin Orthop Relat Res. 2002;(398):75–84.
  7. Shetty A, Kanna RM, Rajasekaran S. TB spine—Current aspects on clinical presentation, diagnosis, and management options. Semin Spine Surg. 2016;28:150
  8. Garg RK, Somvanshi DS. Spinal tuberculosis: a review. J Spinal Cord Med. 2011;34(5):440-54.
  9. Jia C, Gao J, Liu F, et al. Efficacy, safety and prognosis of treating neurological deficits caused by spinal tuberculosis within 4 weeks’ standard anti-tuberculosis treatment: A single medical center's experience. Exp Ther Med. 2019:519-526. doi:10.3892/etm.2019.8253.
  10. Cao G, Rao J, Cai Y, et al. Analysis of Treatment and Prognosis of 863 Patients with Spinal Tuberculosis in Guizhou Province. Biomed Res Int. 2018;2018. doi:10.1155/2018/3265735.
  11. Jiang T, Zhao J, He M, Wang K, Fowdur M, Wu Y. Outcomes and treatment of lumbosacral spinal tuberculosis: A retrospective study of 53 patients. PLoS One. 2015;10(6):1-15. doi:10.1371/journal.pone.0130185.
  12. Liu Z, Wang J, Chen GZ, et al. Clinical Characteristics of 1378 Inpatients with Spinal Tuberculosis in General Hospitals in South-Central China. Biomed Res Int. 2019;2019. doi:10.1155/2019/9765253.
  13. Rathod TN, Sathe AH, Marathe NA. It’s Never Too Late: Neurological Outcome of Delayed Decompression in Tuberculosis of Spine. Glob Spine J. 2021;11(5):716-721. doi:10.1177/2192568220922209.
  14. Rasouli MR, Mirkoohi M, Vaccaro AR, Yarandi KK, Rahimi-Movaghar V. Spinal tuberculosis: diagnosis and management. Asian Spine J. 2012 Dec;6(4):294-308. doi: 10.4184/asj.2012.6.4.294. Epub 2012 Dec 14.
  15. Jain AK, Kumar J. Tuberculosis of spine: neurological deficit. Eur Spine J. 2013 Jun;22 Suppl 4(Suppl 4):624-33.

How to Cite

Setiajaya, J. (2022). Prevalence and prognosis from the disability related to spinal tuberculosis: a systematic review. Indonesia Journal of Biomedical Science, 16(1), 55–60. https://doi.org/10.15562/ijbs.v16i1.384

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