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Beneficial health effects of butterfly pea (Clitoria ternatea): A literature review


The butterfly pea, a plant belonging to the Fabaceae family, is found extensively globally, particularly in tropical and subtropical regions. Locals often utilize butterfly pea (Clitoria ternatea) as a medicinal resource due to its flavonoid compounds, predominantly present in its roots, leaves, and flowers. Flavonoids, which are phenolic compounds, possess antioxidant properties that safeguard against cell damage caused by free radicals. This review of the literature aims to explore the various health benefits associated with the butterfly pea. The approach conducted in writing this article involves sourcing information from diverse journal articles available online, including Google Scholar, PubMed, and ScienceDirect. Based on the review, butterfly pea flowers are recognized for their advantageous qualities, including antioxidants, anti-inflammatory, antidiabetic, antihyperlipidemic, hypoallergenic, antitussive, anti-aging, and antidepressant properties.



  1. Oguis GK, Gilding EK, Jackson MA, Craik DJ. Butterfly pea (Clitoria ternatea), a cyclotide-bearing plant with applications in agriculture and medicine. Vol. 10, Frontiers in Plant Science. 2019.
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  6. Saritani ATB, Wiraguna AAGP, Maker LPII. Clitoria ternatea L. extract cream 5% inhibited the increase of MMP-1 levels and decrease of collagen amount in wistar rats (Rattus norvegicus) dermic skin exposed to ultraviolet B. Neurol Spinale Med Chir. 2021;4(3).
  7. Indrayani KE. Efek Antiinflamasi Topikal Ekstrak Etanol Bunga Telang (Clitoria ternatea L.) Pada Kulit Mencit Terinduksi Karagenin. Fak Farm Univ Sanata Dharma, Yogyakarta. 2020;
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  9. Ma’ruf NQ, Hotmian E, Tania AD, Antasionasti I, Fatimawali, Tallei TE. In silico Analysis of the Interactions of Clitoria ternatea (L.) Bioactive Compounds against Multiple Immunomodulatory Receptors. In: AIP Conference Proceedings. 2022.
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  11. Nugraha AP, Rahmadhani D, Puspitaningrum MS, Rizqianti Y, Kharisma V, Ernawati DS. Molecular docking of anthocyanins and ternatin in Clitoria ternatea as coronavirus disease oral manifestation therapy. J Adv Pharm Technol Res. 2021;12(4).
  12. Adhikary R, Sultana S, Bishayi B. Clitoria ternatea flower petals: Effect on TNFR1 neutralization via downregulation of synovial matrix metalloproteases. J Ethnopharmacol. 2018;210.
  13. ALshamrani SM, Safhi FA, Mobasher MA, Saleem RM, Alharthi A, Alshaya DS, et al. Antiproliferative Effect of Clitoria ternatea Ethanolic Extract against Colorectal, Breast, and Medullary Thyroid Cancer Cell Lines. Separations. 2022;9(11).
  14. Pakpahan FD, Rahmiyani I, Sukmawan YP. Wound Healing Activity of the Clitoria ternatea L. flower Ethanolic extract gel preparation in Diabetic Animal Model. Res J Pharm Technol. 2023;16(1).
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  17. Devi BP, Boominathan R, Mandal SC. Anti-inflammatory, analgesic and antipyretic properties of Clitoria ternatea root. Fitoterapia. 2003;74(4).
  18. Parimaladevi B, Boominathan R, Mandal SC. Evaluation of antipyretic potential of Clitoria ternatea L. extract in rats. Phytomedicine. 2004;11(4).
  19. Hutapea CM, Subchan P, Putra A. Clitoria ternatea Flower Extract-Based Gel Elevates TGF-β1 Gene Expression and Collagen Density in UVB-Induced Collagen Loss Rat Skin. J Kedokt Brawijaya. 2023;
  20. N. S NA, Muniroh M, Kusumaningrum N, P M FE, Yuniati R. Clitoria ternatea L. Extract as Adjuvant Therapy on Reducing IL–6 Levels in Reversal Reaction. Biosaintifika J Biol Biol Educ. 2023;15(1).
  21. Swathi KP, Jayaram S, Sugumar D, Rymbai E. Evaluation of anti-inflammatory and anti-arthritic property of ethanolic extract of Clitoria ternatea. Chinese Herb Med. 2021;13(2).
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  23. Kavitha R. Biochemical studies on the effect of ethnolic extracts of Trichosanthes dioica and Clitoria ternatea in Streptozotocin induced diabetic male wistar rats. Int J Pharm Sci Res. 2018;9(11).
  24. Solanki YB, Jain SM. Antihyperlipidemic activity of Clitoria ternatea and Vigna mungo in rats. Pharm Biol. 2010;48(8).
  25. Subchan P, Putri RS, Muna NI, Magdalena C. Ekstrak Bunga Telang ( Clitoria ternatea L . ) Menghambat Peningkatan Ekspresi Gen MMP-1 pada Kulit Tikus Wistar yang Terpapar Sinar Ultraviolet B. J Midwifery Heal Sci. 2022;(August).
  26. Alnaz ARM, Ridha R, Nasution RFG, Nasution AH, Ichwan M. In vitro study of anthelmintic effect of butterfly pea (Clitoria ternatea) flower aqueous extract on Tubifex tubifex. In: IOP Conference Series: Earth and Environmental Science. 2021.
  27. Nirmal SA, Bhalke RD, Jadhav RS, Tambe VD. Anthelmintic activity of Clitoria ternatea. Pharmacologyonline. 2008;1.
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  29. Rizkawati M, Rizkita LD. Potensi Aktivitas Antibakterial Ekstrak Bunga Telang (Clitoria Ternatea). J Sains dan Kesehat. 2023;5(1).
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  31. Parvathi M, Ravishankar K. Evaluation of antidepressant, motor coordination and locomotor activities of ethanolic root extract of Clitoria ternatea. J Nat Remedies. 2013;13(1).

How to Cite

Santosa, D. F. . (2023). Beneficial health effects of butterfly pea (Clitoria ternatea): A literature review. Indonesia Journal of Biomedical Science, 17(2), 244–247.




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