Titin Isna Oesman, A. Manuaba, N. Adiputra, D.P. Sutjana

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Part body component of a car is the finished product component that is mainlyproduced by the big press machine. In the production process of part body component of acar in the stamping plant division, the manual task is performed by two operators to feedingthe material sheet into the big press machine simultaneously. After the knobs were pressedtogether, the big press machine started to stamp the material sheet and the outcoming productis taken by the next operator. This task is performed repeatedly until it is the last one.Manual and comprehensive task that combined with speed in operating the big press machinecause who muscular tension which at the end could cause muscular complaints and prematurefatigue, that could decrease production and productivity.The current study of ergonomic intervention on stamping process of part bodycomponent of car was conducted in order to determine whether ergonomic intervention couldimprove the work quality, satisfaction and time efficiency in the stamping process.The subjects of study were 10 persons that were taken randomly. It was designedexperimentally with treatment by subject design. The method of data collection was byquestionnaire distribution and direct measurement of subject’s condition, time of stampingprocess and work environment before and after intervention. The Shapiro Wilk test showedthat all of the data had normal distribution and was followed by t-paired for data of workquality, work satisfaction, time efficiency, and the environment data. The significance level isset at 5%.The research result showed that work quality was improved (muscular complaints wasdecreased by 6,65%, fatigue was decreased by 5,47% and work boredom was decreased by5,87%), work satisfaction was improved up to 6,43%, time efficiency of stamping processwas improved up to 10,7%, the production was improved up to 2,59% and productivity wasimproved up to 32,65% as well as company’s profit was increased up to 3,95%.Hence, the study concludes that ergonomic intervention in the production process ofpart body component of car in the stamping plant division could improve work quality, worksatisfaction and time efficiency.

Ketut Suega, I M Bakta, AAG Sudewa D., Ketut Suata

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Iron is an essential nutrient for every living cells because of it role as molecule fortransport of oxygen, as well as DNA synthesis through synthesis of ribonucleotidereductase. Iron deficiency anemia patients, especially pregnant women and children aremore susceptible to infection because of deterioration of their immune response. This wassupported by findings of decreased in phagocytic activities of white blood cells and Tcelllymphocyte proliferation impairment. Iron deficiency anemia (IDA) patients alsoaffect working capacities hence diminishing working outcomes. Although the underlyingmechanism of immune defect in iron deficiency anemia is not clearly understood,multifactor events considered play their contributing roles such as abnormality ofribonucleotide reductase enzym, impairment of T-cell proliferation and activities, alteredcytokine production of IL-2 and IFNγ .The study was done to asses the relationship of IL-2 and gamma IFN withinfection in IDA patients on lymphocyte culture supernatant of IDA patients. Study wasconducted on cross-sectional analytic design. Sixty-four iron deficiency anemia patientstreated in Sanglah General Teaching Hospital were recruited, and 31 (48.4%) out of 64IDA patients were man and 33 (51.6%) women, have been selected for the study. Thisstudy found 17 (26.7%) IDA patients with infection, aged 38 ± 14.48 years and 47(73.3%) IDA patients without infection, with age average of 40.5 ± 14.4 years. Allvariables of data characteristics examined did not indicate any statistical significantdifference between group of IDA patients with infection and those without infection. Theaverage level of hemoglobin between the two groups did not differ statistically. Similarresult was obtained if samples were differentiated into severe (Hb< 7g/dl) and mildanemia. The study also revealed that there were no differences of cytokine level observedbetween older and younger age (upper and below 44.5 years) in IDA patients withinfection and without infection. Furthermore, no differences of cytokine level were foundbased on gender between IDA male 10.9 (8.60 – 12,65) (pg/l) patients and IDA femalepatients 10.6 (7.50 – 13.43) (pg/l) with Z -0.490, p =0.624. Nevertheless, significantdifferences were noted between supernatant of IL-2 and IFNγ in IDA patients withinfection when compared to IDA patients without infection (Z= - 2.509, p= 0.012 forsupernatant IL-2; and Z= -2.569, p= 0.010 for supernatant IFNγ ).The study conclusion is that level of IL-2 and IFNγ from lymphocyte culturesupernatant of patient suffered from IDA with infection is significantly lower whencompared to IDA patient without infection. It therefore summarized that lower level ofIL-2 and gamma IFN in patients suffered from iron deficiency impaired their immune response to certain infections therefore this findings support the theory that IDA patientsmore susceptible to get infected.

Made Wiryana, Ketut Suastika, Hari Bagianto, Made Bakta

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Hyperglycemia and insulin resistance are common in critically ill patientsin the ICU, although they have not previously had diabetes. It has been reportedthat pronounced hyperglycemia may lead to complications in such patients, andcause the reactive oxygen species (ROS) production, although controlled trial dataare still lacking. The current debatable issue, focusing on whether the intensiveinsulin therapy, aimed at normalizing blood glucose, may improve patients’prognosis. Then, the debate is mainly about the time to start the therapy,and target of blood glucose level. Therefore, this research is mainly designed andaimed at knowing the difference between intensive insulin therapy andconventional insulin therapy on the increase of superoxide dismutase (SOD),decrease of cytokine production (TNF-α and IL-6), increase of albumin level, andevent of SIRSThis study was carried out in a randomly pre and post-test control groupdesign, involving 40 adult patients being nursed through the ICU Sanglah hospitalDenpasar. They were randomly assigned to receive intensive insulin therapy, inwhich blood glucose was decreased and maintained at the level between 80-110mg/dl, or conventional insulin therapy in which the insulin was infused only if theblood glucose level exceeded 215 mg/dl, decreased and maintained then at thelevel between 180-200 mg/dl.The result of the study showed that there was (1) significant increase ofSOD mean level (370. 70 vs 98.50 U/gHb, p=0.001); (2) no significant decreaseof TNF-α mean level; (3) significant decrease of IL-6 mean level (10.26 vs 2.25;p=0.023); (4) significant increase of albumin mean level ( 0.62 vs 0.22); (5)significant decrease of SIRS (10 % vs 40 %, p=0.000) on intensive insulin therapygroup compared to conventional insulin therapy group. It can be concluded thatintensive insulin therapy could maintain blood glucose level between 80 – 110mg/dl, increase SOD level, decrease IL-6 level, increase albumin level, anddecrease SIRS on hyperglycemia in critically ill ICU patients.